![]() ![]() Exactly why glucose use is affected in Alzheimer’s is not clear. This impaired use of glucose is paralleled by a decline in scores on cognitive tests. This is because so much glucose is absorbed by muscle cells that little is left for the brain.Īlzheimer’s disease is characterized by a progressive decline in the rate of glucose metabolism in the brain. ![]() We know, for example, that a rapid drop in blood glucose, as can be precipitated by an overdose of insulin, quickly causes a deterioration in cognitive performance. It stands to reason that any sort of inhibition of this glucose metabolism can have a profound effect on brain function. What has no mass, doesn’t occupy space, has no mobility, cannot be touched and yet exists? A thought! And what a mysterious thing it is! Just about all we know for sure is that it is created in the brain and that there is an energy requirement to generate it. Whenever we think, the brain “burns” more glucose, which is its main fuel supply. ![]()
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